There is a controversy wheter central pontine myelinolysis can complicate either hyponatremia or its rapid correction. Central pontine myelinolysis cpm is the most severe neurological complication after liver transplantation and apparently is not. Central pontine and extrapontine myelinolysis after correction of severe hypoglycemia. It is predominately iatrogenic treatmentinduced, and is characterized by acute paralysis, dysphagia difficulty swallowing, dysarthria difficulty speaking, and other neurological symptoms. Convulsiones, estado mental alterado mielinolisis pontina central 82. Brin, md, and the spasticity study group rationale botulinum toxin type a btxa is an effective treatment for focal or segmental muscle. Early diagnosis of central pontine myelinolysis with diffusionweighted imaging. Clinical analysis of central pontine myelinolysis after. Central pontine myelinolysis cpm is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons an area of the brainstem. Files are available under licenses specified on their description page. Mielinolisis extrapontina secundaria a hiponatremia por crisis. Central pontine myelinolysis radiology reference article. Pdf hyponatraemia, pontine myelinolysis and rhabdomyolysis. Chronic alcoholism or rapid correction of hyponatremia was present in over 75% of cases.
Ruizmiyares and others published hyponatraemia, pontine myelinolysis and rhabdomyolysis find, read and cite all the research you need on researchgate. No serum levels of bcomplex vitamins was done, that would have. Central pontine myelinolysis is a rare neurological alteration, of unknown etiology, which is observed mainly in alcoholic chronic patients or with chronic diseases. Pdf mielinolisis central pontina en trasplante hepatico. Pdf mielinolisis pontina central e hiponatremia perioperatoria.
All structured data from the file and property namespaces is available under the creative commons cc0 license. To discuss the etiology, diagnosis and treatment of central pontine myelinolysis cpm by analyzing 4 cases of our center and 26 cases reported by others in our country. The importance of magnetic resonance imaging in diagnosis. A mielinolise pontina central mpc e uma doenca desmielinizante aguda. We analyzed the clinical feature, diagnosis and treatment of 4 cpm cases and then compared them with 26 cpm cases reported between 2000 and 2010. Antemortem computed tomography ct had been performed in nine, and ante or postmortem magnetic resonance mr imaging in 11. Dosing, administration, and a treatment algorithm for use. Pdf central pontine myelinolysis is a demyelinating lesion in the basis pontis which in most cases is caused by a rapid correction of hyponatremia.
Mediators of inammation theprevalenceofanyretinopathyindiabeticpatientsismore than %. Central pontine myelinolysis as a complication of the disease due to burns. Leucemia mieloide cronica e neoplasie mieloproliferative croniche ph negative i tumori ematologici. Sequential observation of movements disorders and brain images in the case of central pontine myelinolisis and extrapontine myelinolsis. Mielinolisis extrapontina en paciente con hipernatremia. Chronic hyperglycaemia drew metabolic and haemodynamic derangements, such as. As such the condition is described in the osmotic demyelination syndrome article.
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